Cowdry type inclusion bodies: NExt oral pathology
Cowdry type inclusion bodies are distinct microscopic structures that can be observed in cells infected with certain viruses. These inclusion bodies were first described by Dr. Ernest A. Cowdry, and they are classified into two types: Cowdry type A and Cowdry type B. These inclusions are important diagnostic features in the field of virology and pathology. 1. **Cowdry Type A Inclusion Bodies:** - **Composition:** Cowdry type A inclusions are eosinophilic, homogenous nuclear inclusions. - **Location:** They are found within the nuclei of infected cells. - **Associated Viruses:** Commonly associated with herpes simplex virus (HSV) and varicella-zoster virus (VZV). 2. **Cowdry Type B Inclusion Bodies:** - **Composition:** Cowdry type B inclusions are basophilic, granular inclusions. - **Location:** They are located in the nucleus or cytoplasm of infected cells. - **Associated Viruses:** Commonly associated with adenoviruses, especially adenovirus serotypes 1, 2, and 5.