Pulp tissue development
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🧬 Pulp Tissue Cells & Tooth Bud Development
🔬 Histology of Pulp Tissue
- Odontoblasts: Line the outermost layer of the pulp; responsible for dentin formation.
- Fibroblasts: Most abundant cells; secrete collagen and maintain extracellular matrix.
- Macrophages: Immune defense cells that remove debris and bacteria.
- Dendritic Cells: Act as antigen-presenting cells; part of immune surveillance.
- Mast Cells & Plasma Cells: Involved in inflammatory response and antibody production.
🦷 Development of the Tooth Bud
- Initiation Stage: Begins around the 6th week of embryonic life; formation of dental lamina.
- Bud Stage: Proliferation of dental lamina into the underlying ectomesenchyme to form a tooth bud.
- Cap Stage: Enamel organ, dental papilla, and dental sac become distinct.
- Bell Stage: Morphodifferentiation and histodifferentiation occur; enamel and dentin-forming cells are defined.
- Apposition and Maturation: Deposition and mineralization of enamel and dentin.
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